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A patient satisfies the diagnostic criteria for FMS if the following 3 conditions are met: Although the precise mechanisms contributing to the pathophysiology of FMS remain to be fully elucidated, it is thought that patients with fibromyalgia have impaired endogenous analgesic systems, in particular suboptimally functioning descending inhibitory pathways, which normally function to ameliorate pain as well as abnormal pain processing

The clinical need must be considered in addition to any potential adverse outcomes for the infant

In the future, AOD 9604 is expected to become an important drug in the field of local fat reduction, providing a safer and more effective treatment option for obese patients

COA will be published here before this batch ships