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Nat Rev Gastroenterol Hepatol 8(7):385394

Many of the peptides included in FDAs update to category 2 were extremely popular amongst patients and practitioners in the functional medicine, regenerative medicine and anti-aging space

The main risks include gastrointestinal side effects (nausea, vomiting, diarrhoea), increased risk of nutritional deficiencies due to combined appetite suppression and reduced stomach capacity, and potential hypoglycaemia in patients taking certain diabetes medications

This transporter effectively imports oxidized glutathione (GSSG) into the ER while exporting the reduced variant (GSH), thereby fine-tuning the oxidative ratio inside the lumen