Greenberg LH, Momary H
The native GLP-1 peptide is a derivative of the proglucagon gene and is principally synthesized by the L-cells of the ileal mucosa
Here's a comprehensive list: Chemical Reagents Fmoc-protected amino acids Coupling reagents (e.g., HBTU, HATU, or DIC) Solvents (e.g., DMF, DCM, NMP) Deprotection reagents (e.g., piperidine) Cleavage cocktail components (e.g., TFA, water, triisopropylsilane) Equipment Peptide synthesizer (automated or manual) HPLC system for purification Mass spectrometer for peptide characterization Lyophilizer for freeze-drying Rotary evaporator Analytical balance Consumables Solid support resin (e.g., Wang resin) Reaction vessels Filtration apparatus HPLC columns Having these materials on hand is crucial for the successful preparation of BPC 157 powder
Richie, J.P., Nichenametla, S., Neidig, W