Most patients were Caucasian (78.7% and 78.4% in each cohort, respectively), as recorded in the electronic health record
Available test results have revealed that stress and the activation of pro-inflammatory cytokines noted in depression can increase the activity of indoleamine 2,3-dioxygenase (IDO) in the peripheral tissues and the brain, leading to increased degradation of tryptophan and towards synthesis of detrimental tryptophan catabolites (TRYCATs) (Maes et al
Essential Supplements for Bone Protection A targeted supplement regimen can make a significant difference in maintaining bone density: Calcium + Vitamin D3 Daily requirement : 1,000-1,200mg calcium and 2,000-5,000 IU vitamin D3 Best forms : Calcium citrate (more easily absorbed than calcium carbonate), vitamin D3 (cholecalciferol) Timing : Split calcium doses throughout the day for better absorption Vitamin K2 Daily requirement : 100- 200 mcg Function : Directs calcium to your bones rather than soft tissues and blood vessels Forms : MK-7 form has better bioavailability than MK-4 Magnesium Daily requirement : 320-420mg daily Forms : Magnesium glycinate or malate for better absorption and less digestive discomfort Benefits : Works synergistically with calcium and vitamin D Collagen Peptides Daily requirement : 10-15g Function : Provides the protein matrix upon which bone mineralization occurs Bonus : Also supports skin, hair, and joint health 2
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