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Objective measurements (EEG, cardiovascular, and respiratory parameters) and subjective ratings (visual analog scales, awakening times) showed, assessed by Mann-Whitney U test, a normalization of severely disturbed sleep to normal sleep patterns

To reach their full anti-cancer potential, cytotoxic agents like doxorubicin, epirubicin, paclitaxel, docetaxel, cisplatin, carboplatin, antimetabolites, 5-fluorouracil, capecitabine, and targeted therapies like trastuzumab and CDK4/6 inhibitors rely on precise dosing or predictable metabolic pathways, among other factors (201)

Safety monitoring is also crucial while probiotics and FMT have been safe in trials so far, there is a theoretical risk of introducing infections or causing undesired immune reactions, especially in patients with immune dysfunction (like those on MS immunosuppressants)