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Glutamatergic synapses are structurally and biochemically complex because of multiple plasticity processes: long-term potentiation, long-term depression, short-term potentiation and scaling

The magnitude and the long-term clinical impact of these effects is still being evaluated, but the data available suggest GLP-1 RAs (and likely SGLT2 inhibitors) play a main role in the treatment of NAFLD

In addition, a large observational study suggested that the GLP-1 RA semaglutide lowered the incidence and recurrence of AUD compared with other anti-obesity drugs

Certain medications and supplements may interact with glutathione, affecting its efficacy or causing adverse reactions