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136 In addition, acquired astrocytopathies are prominent in hepatic encephalopathy (in which astrocytes lose their homoeostatic capabilities 137 ) and in neuromyelitis optica, in which the astrocyte protein, AQP4 is the subject of autoimmune attack, leading to dysfunction and death of astrocytes resulting in pronounced inflammation and degeneration of neural tissue

Celeste Simon

[DOI] [PubMed] [Google Scholar] 84.Zhao N, Zhuo X, Lu Y, Dong Y, Ahmed ME, Tucker D, et al

For these reasons, we suggest selective targeting, proper timing and dose, and the design and construction of nanoparticles as delivery vehicles [17, 141]