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Pre-specified outcomes The primary outcome was defined as the annual rate of acute healthcare utilization (number of events per year of follow-up): calculated as the sum of urgent care visits, Emergency Department visits, and hospitalizations divided by the duration of follow-up

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In this population, GLP-1 agonist use was associated with a 15% reduced risk of developing dry AMD and a 20% lower risk of wet AMD compared to other antidiabetic medications

However, we disagree that weighting the ASM cost performance category at 30 percent and incrementally raising it over time would reward the right behaviors