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less data on gallbladder effects Naltrexone-bupropion (Contrave): Targets central appetite regulation

Variants in genes such as GLP1R (rs6923761), GIPR (rs1800437), and FTO (rs9939609) affect how efficiently your cells bind and respond to these medications, potentially determining whether you'll need higher or lower doses

2020;43:S98S110

In addition to their role in insulin secretion, GLP-1R agonists can also contribute to weight management, decrease the potential for cardiovascular diseases and protect beta cells