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The ongoing research into the long-term effects of cagrilintide and tirzepatide is crucial, as it will help determine their place in the broader landscape of diabetes and obesity management

Their large peptide structure (Figure 1) makes them prone to enzymatic degradation, lowering bioavailability, and can trigger immunogenicity causing anti-drug antibodies (ADAs)

Understanding this mechanism is essential for both clinicians and patients, as it underscores that constipation is a predictable pharmacologic effect rather than an idiosyncratic reaction

It would appear that Farah was prepared to take Salazars advice about the legal use of a supplement via an IV drip, which Salazar had found would improve his performance