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doi: 10.3171/2016.2.jns1633 141 PatelBGAhmedKAJohnstonePAYuHHEtameAB

Avoid injecting into areas with visible veins, bruises, scars, or skin abnormalities

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GSH-triggered prodrugs Because intracellular GSH levels are typically elevated in tumor cells relative to normal tissues, this redox imbalance has been exploited as a tumor-associated trigger for prodrug activation and selective cytotoxicity 214