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Beyond that, theres no established best time of day
Tachyphylaxis is contingent upon a full 24-hour exposure, as evidenced by a study in which rats treated with liraglutide (with half-life of 11 15 hours) twice daily for 14 days had markedly diminished gastric emptying while those treated with exenatide (with half-life of 2 3 hours) twice daily over the same period still displayed a profound reduction in gastric emptying, although both compounds had similar effects on body weight reduction (158)
doi: 10.1016/j.cell.2015.02.047 275 YanQ.WangW.FanZ.WeiY.YuR.PanT.et al
Precision medicine in fatty liver disease/non-alcoholic fatty liver disease
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