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The importance of oxidative stress in the testicular toxicity associated with arsenic was emphasised by the ability of ascorbate to reverse these changes.119 Similarly, vanadate is a testicular toxicant that induces lipid peroxidation in the testes along with significant suppression of testicular SOD and catalase and the disruption of 3- and 17-hydroxysteroid dehydrogenase activities.120 In addition to the above, Table 1 lists a wide variety of different industrial and environmental toxicants that are all capable of compromising male fertility by inducing a state of oxidative stress in the testes