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Gomez D, Blumenschein G, Lee J, Hernandez M, Camidge R, Doebele R, Gaspar L, Karam J, Kavanagh B, Louie A, Palma D, William W, Zhang J, Swisher S , Heymach J

The GnRH receptor is also found in certain cancers, and the reduction in circulating estrogen slows the growth of hormone receptor-positive tumors such as ovarian cancer 117 , prostate cancer 118 , and breast cancer 119,120,121

Your provider will determine the appropriate off-period for your situation

Up to 55% of patients developed anti-drug antibodies [65], which were associated with systemic allergic reactions in approximately 5% of cases and injection-site hypersensitivity, including anaphylaxis, which necessitated early trial termination [66, 67]