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While some suggest applying a cold pack near (not on) the injection site before injection, evidence for this approach is limited

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HLC cultures were incubated with conventional probe substrates for CYP3A4 (6 M midazolam), CYP2C9 (10 M diclofenac), and CYP2D6 (10 M dextromethorphan) for 2 hours

They may recommend that you dispose of that pen and start a new one before your next weekly injection, especially if Ozempic was left, say, out in the car and was exposed to extreme temperatures