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Considering the high potency of ecnoglutide, it might also serve as a viable option for individuals who do not achieve sufficient weight reduction with existing GLP-1 receptor agonists at their approved doses or need to achieve a larger reduction in bodyweight, Ji added

Although Mounjaro is not FDA-approved for weight loss, people who take Mounjaro for their diabetes may lose weight, and some doctors prescribe Mounjaro off-label for weight loss

DPP-4 inhibitors can also cause several side effects, such as headache, nasopharyngitis, nausea, arterial hypertension, heart failure, pancreatitis and inflammatory bowel disease, and various skin reactions (pruritus, bullous pemphigoid, rash, angioedema and photosensitivity)