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The peptide is indicated for therapy in overweight or obese adults, in conjunction with a reduced calorie diet and increased physical activity, as well as in obese adolescents aged 12-17 [8]
Neuron 112, 12651285.e10
Side effects with Wegovy 7.2 mg The STEP UP trial found that side effects were somewhat more common at the higher dose: 2 GI side effects: 70.8% (7.2 mg) vs 61.2% (2.4 mg) Dysaesthesia (tingling/numbness): 22.9% (7.2 mg) vs 6.0% (2.4 mg) Discontinuation due to side effects remained low at 3.3% The dysaesthesia finding is notable, though 85.7% of cases resolved while continuing treatment
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