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GLP-1 medications, peptides, NAD, and even exosome therapies have moved from niche clinical research into popular discussion
Second, long-term outcomes are still being studied
The post hoc analysis of pooled data from the Semaglutide Treatment Effect in People with Obesity (STEP) 1, 2, 3, and 5 trials indicated that semaglutide treatment at 2.4 mg did not increase the risk of depressive symptoms or suicidal ideation compared to placebo, while demonstrating a statistically significant yet clinically negligible decrease in depressive symptoms [75]
What has become increasingly clear is that GLP-1 receptors are expressed throughout the bodyin the brain, heart, endothelium, pancreas, and immune cellsmaking this pathway a powerful modulator of systemic aging processes
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