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When to talk to your provider Contact your provider if you experience no appetite suppression after 4 weeks of consistent use, if side effects worsen rather than improve over time, if you develop mouth sores or persistent oral irritation, or if your results plateau significantly after previously good progress

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Eating behavior affects the effect more than most people think Even though the medication helps a lot, eating behavior can both amplify and dampen the effect

In astrocytes lacking GLP-1R, the increase in FGF21 is associated with improved systemic glucose homeostasis and memory formation