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While RYBELSUS is not for weight loss, you may also lose some weight is not for weight loss, you may also lose some weight At 6 months, in a medical study, people who weighed an average of 202 pounds, on average, lost around: 8.4 pounds while taking 14 mg of RYBELSUS 8.1 pounds while taking 25 mg of JARDIANCE The average weight loss was about the same in people taking 14 mg of RYBELSUS and in people taking 25 mg of JARDIANCE