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Consequently, the gutkidney axis can be understood as a unified framework, mediated by immune and metabolic pathways, that links gut immunity with microbial metabolism, thereby opening new avenues for immune-modulatory strategies beyond traditional pharmacological approaches ( 3.2 Gut barrier dysfunction and endotoxin translocation The gut barrier is a complex protective system comprising physical, chemical, microbial, and immune barriers, with tight junction proteins being a critical element ( Under normal conditions, protected by tight junction proteins, the gut barrier prevents the passage of intestinal pathogens ( 3 which is hydrolyzed to NH 4 OH, raising the intestinal pH

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The drug can also reduce appetite by slowing the rate at which the stomach empties, and possibly through effects on the brain

[40], have explored the impact of radio frequency electromagnetic waves (RF-EMW) on human health, noting a potential correlation between long-term exposure and reduced body weight