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PMNR and RFBS contributed to writing of the original draft

B12 fortified foods, such as cereals, nondairy milk, and nutritional yeast

Reported or theoretical concerns may include: Injection-site reactions Transient headache Nausea or mild gastrointestinal discomfort Fatigue or energy fluctuations Unknown long-term effects Potential immune reactions or quality concerns with non-regulated products Theoretical concerns include potential over-suppression of inflammatory responses at high concentrations, so monitoring markers such as CRP and IL-6 during extended use may be recommended by a qualified clinician

Chilton, W., & Charchar, F