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Not one was a true biological non-responder

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While no formal statistical testing was performed due to the small sample size, the study demonstrated numerically higher remission rates at week 8 in the abrilumab groups overall (12.9%) compared to placebo (0%), with individual dose results of 10.0% (21 mg), 16.7% (70 mg), and 11.1% (210 mg), alongside numerically higher response rates with 210 mg (66.7%) and mucosal healing rates with 70 mg and 210 mg (33.3% and 44.4% respectively), confirming the favorable safety profile observed in the global study with no progressive multifocal leukoencephalopathy or deaths reported (48)

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