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Statistical significance was determined using two-tailed Students t test through GraphPad Prism5 software unless otherwise mentioned

Light/UV radiation stress Light stress, arising from insufficient or excessive irradiance, is a major abiotic factor that disrupts fundamental physiological and molecular processes in plants, including photosynthesis, carbon fixation, and redox homeostasis (Roeber et al

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The active metabolites of Pycnogenol, particularly the smaller phenolic acids and the gut-derived metabolite M1, can enter the central nervous system