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lying down can worsen nausea Ginger tea or peppermint can help mild nausea for some people For constipation: Increase fibre intake gradually (not suddenly that can make things worse) Drink plenty of water throughout the day Gentle physical activity helps keep things moving For injection site reactions: Rotate injection sites (abdomen, thigh, upper arm) Ensure the medication is at room temperature before injecting Use proper injection technique your prescriber or pharmacist can demonstrate this For skin sensitivity: This generally resolves without treatment If bothersome, loose-fitting clothing and avoiding very hot showers may help Report persistent or worsening symptoms to your prescriber When to seek medical attention Most retatrutide side effects are mild and self-limiting