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Several basic molecular and cellular mechanisms are shared among brain diseases, such as neuroinflammation, oxidative stress, excitotoxicity, neurodegeneration, disorders of neurogenesis, dysfunction of neurotrophic factor systems, which are most prominent in specific brain structures associated with different brain diseases [104, 105]

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Absolute contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, and severe hypersensitivity to GLP-1 agonists