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bioRXiv preprint

Theriogenology 65 , 14071421 (2006)

However, chronic inflammation can contribute to the development of chronic diseases such as arthritis, diabetes, and heart disease

We have previously identified that Sita (i.e., an DPP4 inhibitor) therapy significantly suppressed the DPP4 activity in circulation which, in turn, markedly increased circulating and tissue levels of SDF-1 and GLP-1 in setting of organ ischemia in rodent [29-32]