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Additionally, a family of enzymes expressed on the outer membrane of cells, gamma-glutamyl transpeptidases (GGTs), is involved in recycling extracellular glutathione, thereby contributing to de novo intracellular glutathione biosynthesis and ROS detoxification [14]

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For patients whose cancers do not respond to conventional therapy, the discovery of uncommon anti-tumor lymphocytes that can infiltrate and aid in the destruction of metastatic solid epithelial tumors could promote the development and efficacy of personalized cancer immunotherapies [228]

Utilizing the recent advancements in science, a peptide similar to Epithalamin was synthesized and titled Epithalon. Epithalon is derived from a naturally occurring peptide belonging to both the pineal gland and eye retina