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Manufacturing standards and quality controls differ from those applied to FDA-approved products like Ozempic and Wegovy

In the normal renal function group, one participant had a clinically significant vital sign abnormality (increased blood pressure) and one had a clinically significant ECG abnormality, with both reported as resolved mild TEAEs

Small trials run in a single region, funded or supported by the maker, tend to report larger effects than big independent ones, partly because small studies that happen to land a positive result are the ones that get published while the null ones quietly disappear, and partly because looser blinding and outcome-grading let optimism leak into the numbers

31,32 Foods with high concentrations of fructose include honey