When, however, significant enrollment, utilization, cost, and acuity changes began to emerge early in the COVID-19 public health emergency, CMS allowed states to modify managed care contracts, and many states implemented COVID-19 related risk corridors (where states and health plans agree to share profit or losses), allowing for the recoupment of funds
Investigations of already-approved DORA drugs are also expanding into other populations
After screening titles and abstracts, 64 studies were selected for full-text review, and 41 articles were ultimately included in this review, including 12 randomized controlled trials, 16 observational studies, and 13 mechanistic or preclinical studies
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