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Maintaining the weight loss achieved through medicationvia diet, exercise, and behavioral supportbecomes the focus during pregnancy and lactation

In comparison, a small molecule like orforglipron is a roughly 16-step convergent organic synthesis from common starting materials (see, e.g., Part I and Part II of a key intermediate synthesis from the Lilly process team)

As well, MCD inhibition leads to reduced triaglyceride content in lipid synthesizing tissues such as the liver

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