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INTRODUCTION Worldwide, an estimated 35 million people suffer from substance use disorders (SUDs) (United Nations Publication, 2020) and 280 million people from alcohol use disorder (AUD) (World Health Organization [WHO], 2018)

However, the subjects in their study were too young (mean age was approximately 33.5 years), and the sample size was inadequate [258]

Grade Study Research Group, Nathan DM, Lachin JM, Balasubramanyam A, Burch HB, Buse JB, Butera NM, Cohen RM, Crandall JP, Kahn SE, Krause-Steinrauf H, Larkin ME, Rasouli N, Tiktin M, Wexler DJ, Younes N, The GSRG

That said, any side effects are typically mild and should always be discussed with your doctor if they become severe, adds Dr