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Although GLP-1 medications have transformed obesity treatment, there remains a significant need for rigorous data examining how these therapies affect fertility and reproductive function in this population. The RESTORE study is currently evaluating semaglutide treatment in girls and women with PMOS and obesity, with the overarching goal of determining whether weight loss and metabolic improvements can restore ovulation and improve reproductive outcomes

Physicians own the medicine

Over time, repeated alcohol exposure leads to neuroadaptations that shift the balance from liking alcohol to wanting it compulsively, even when consumption no longer produces significant pleasure

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