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They talk about which supplements and how much women should take to keep their heart and bones strong, and why you should be careful when taking pain meds

Whats more, its not clear how much the muscle loss caused by the drugs might matter

The evidence, SELECT, n=17,604 First MACE: HR 0.80, 95% CI 0.72 to 0.90 Non-fatal MI: HR 0.72, 95% CI 0.61 to 0.85 Coronary revascularisation: HR 0.77, 95% CI 0.68 to 0.87 All-cause : HR 0.81, 95% CI 0.71 to 0.93 (Lincoff et al, NEJM 2023) Benefit appeared early, before substantial weight loss, supporting a mechanism partly independent of weight reduction

Here, we first discuss the molecular mechanisms through which GLP-1 and GLP-1RAs regulate insulin secretion and maintain glucose homeostasis