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Surprisingly, despite the broad systemic anti-inflammatory actions of GLP-1RAs, much (1001000 fold) lower levels of GLP-1R mRNA transcripts are detected in spleen, thymus, lymph nodes and hematopoietic cell lineages, relative to levels of GLP-1R expression in gut IELs [138, 139], suggesting that a substantial proportion of GLP-1 action on immune cells may be indirect
Maintaining good hydration throughout the day is important, but try to limit fluid intake in the hour before sleep to reduce nighttime disturbances
Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: studies with the antagonist exendin 9-39
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