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Younger patients and those with good skin elasticity typically see better skin tightening

Through GLP-1R activation, Orforglipron enhances glucose-dependent insulin secretion, improves glycemic control, contributes to lipid homeostasis, and reduces appetite and food intake, supporting its clinical use in obesity and type 2 diabetes [2]

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It has also been discovered that GLP-1RA has the potential risk of inducing hypoglycemia, but it only occurs when it is combined with other hypoglycemic drugs (such as sulfonylureas and insulin)