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If part of why youre taking one of these is your heart, that gap isnt small

Arzneimittelforschung 1995;45:872-4

Glucagon-like peptide-1 (GLP-1) agonists have demonstrated a larger effect size than metformin when treating overweight or obesity, including that caused by antipsychotics MD 6 kg (95% CI 10.8 kg to 1.36 kg)

In the self-controlled case series design, use of GLP-1 RAs was associated with a lower incidence rate ratio (IRR) of suicide or suicide attempts one year after treatment initiation (IRR: 0.45