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This is analogous to how 5-Amino-1MQ works in metabolic research-rather than adding a new signal, it removes a brake on an existing one (NNMT inhibition preserves NAD+

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In addition, very few studies have examined coenzyme Q 10 concentrations in tissues other than blood such that the extent to which statin therapy affects coenzyme Q 10 concentrations in the body's tissues is unknown (118, 120, 125)