next gen glp 1 Pharma Giants Bet on Next-Generation GLP-1 Treatments to Sustain Growth The Next Generation Of Weight

Use of glucagon-like peptide-1 receptor agonists, known as GLP-1s, has skyrocketed among adults, but theyve only been approved for children in the last several years

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In pooled analyses of the STEP-HFpEF (Semaglutide Treatment Effect in People with obesity and HFpEF) and STEP-HFpEF-DM trials, GLP-1 RA had consistent beneficial effects on HF-related symptoms, exercise function, and inflammatory markers in patients receiving diuretics with obesity-related HFpEF [82]

The MHRA-approved indication reflects its role as an adjunct to diet and exercise for adults with type 2 diabetes, and it is typically prescribed when other glucose-lowering therapies have not achieved adequate control