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Comparative analysis of the correlation coefficients revealed that negative correlations between ACC Gln levels and Sensory Sensitivity, between rTPJ Gln levels and Sensation Avoiding, and between the Gln/Glu ratio and Sensory Sensitivity were unique to the ASD group: lower values in these neurometabolite measures were associated with increases in the severity of these sensory sensitivity-related symptoms in ASD

The secretome analysis corroborated these findings, showing intracellular accumulation of ER proteins, consistent with markers of ER stress

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