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Five day administration of high-dose IVIg has led to significant clinical improvement in COVID-19 patients, including normalization of oxygen saturation and reduction in inflammatory markers, with all patients recovering from severe symptoms [55]

These include: AMP-activated protein kinase (AMPK) Upon a reduction in energy, AMPK is activated to stimulate energy producing pathways and turn off energy consuming pathways to restore the ATP/ADP ratio

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