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While it is unlikely that GLP-1 and/or GIP contribute to the pathology of type 2 diabetes mellitus, pharmacotherapeutics targeting both GIP receptors and GLP-1Rs in individuals with type 2 diabetes may offer further benefits than GLP-1R agonism alone [34]

Some of the most common ROS are ( symbolizes radical): Superoxide (O 2 ) Hydroxyl Radical (OH) Hydrogen Peroxide Radical (HO 2 ) Peroxyl Radical (ROO 2 ) Alkoxyl Radical (RO) Ozone (O 3 ) Singlet Oxygen ( 1 O 2 ) Hydrogen Peroxide (H 2 O 2 ) Oxidative Stress the imbalance between the production of ROS/free radicals and the bodys ability to quench them

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