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These conditions are all closely related to hypoxia-induced endothelial cell senescence

Venkateshappa C, Harish G, Mahadevan A, Bharath MS, Shankar SK (2012) Elevated oxidative stress and decreased antioxidant function in the human hippocampus and frontal cortex with increasing age: implications for neurodegeneration in Alzheimers disease

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This allows the product to be supplied in multi-dose vials and used for repeated withdrawals, in contrast to preservative-free sterile water which is intended for single use only