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Glutamine is imported into cancer cells via multiple transporters, including the Na + -dependent transporters, system ASC (alanine/serine/cysteine-preferring) that function as obligatory exchangers, and the Na + -coupled neutral amino acid transporters (SNATs), which belong to the SLC38 superfamily (Cha et al., 2018)
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The cost per dose is higher than any supplement format
However, there are lifestyle-related impacts to glutathione IV therapy that makes it less preferable for some patient populations who can benefit most from the compound, which makes it less convenient than alternatives like oral supplementation
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