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Non-saturated bands were selected to perform densitometry quantification using Image J software (Image J 1.4, NIH, United States)

GHK-Cu is a copper peptide widely recognized for its potential anti-aging and tissue-repair properties, and its one of the most extensively studied peptides in skincare and regenerative beauty

The biological objective is to shift efficacy away from Cmax-limited GLP-1 signaling toward exposure- and residence-timedriven pharmacology, while preserving controlled, functionally relevant GIP co-activation

To identify potential connections between the small intestine and the brain, we conducted retrograde trans-monosynaptic tracing by injecting Fluoro-gold (FG, a fluorescent dye) into the small intestinal wall (Supplementary Fig