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Cartilage & Joint Research Kwon and Park, Annals of Clinical and Laboratory Science (2015) Kwon and Park investigated the chondroprotective effects of intra-articular AOD-9604 administration in a rabbit model of osteoarthritis, with and without co-administration of hyaluronic acid

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The accumulation of ROS reduces the expression of SAC-related proteins, compromises their structural integrity, destabilizes SAC function, leads to the loss of core SAC components, and promotes aneuploidy in oocytes (27)

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