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Malozowski et al studied a cohort of 13 patients and found the mean age of affected patients to be 9 with a range of 3 to 16 years old [2]

Furthermore, circRNAs like ciRS-7 act as miRNA sponges, facilitating melanogenic signaling through the STAT3AKTFGF2 axis, thereby integrating ncRNA networks in pigmentation and cytoprotection 104,108

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