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The companies that originally nominated those peptides for that list have since withdrawn their nominations

The authors compare multiple senolytic strategies including FOXO4-DRI, dasatinib plus quercetin, navitoclax, and fisetin, evaluating mechanisms of action, selectivity profiles, and safety considerations for each approach

10.1016/j.eclinm.2022.101821 [DOI] [PMC free article] [PubMed] [Google Scholar] Mori JO, Keegan J, Flynn RL, Heaphy CM (2024) Alternative lengthening of telomeres: mechanism and the pathogenesis of cancer