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[7] [8] When trial results are split by sex, women often lose a greater percentage of body weight than men at the same dose, which is part of why lower dosing is a rational conversation for midlife women rather than a trend

Both medications belong to the same class of drugs called GLP-1 receptor agonists, and taking them concurrently is considered therapeutic duplication. Using both at once increases the risk of severe side effects without providing proven clinical benefits

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25 The dosing schedule was 1000 g daily for 7 days, then 1000 g once per week for 1 month, then 1 1000 g injection monthly for 6 months