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International Journal of Cardiology, 219, 293300

Says Bilchick, This study adds to our knowledge of the effect of these GLP-1 receptor agonists on reducing morbidity, mortality, and now, in this large study, reducing incident atrial fibrillation over the long term. More research is still needed, especially regarding how different GLP-1 medications, doses, and treatment durations affect weight loss, inflammation, glucose control, Afib risk, and long-term cardiovascular health

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The diminished GPX4 activity results in the accumulation of lipid peroxides within mitochondria, triggering ferroptosis